All unbelief is ultimately rooted not in ignorance of the truth but in a resistance to the truth. Romans 1:18-19 clearly states this principle: "For the wrath of God is revealed from heaven against all ungodliness and unrighteousness of men, who by their unrighteousness suppress the truth. For what can be known about God is plain to them, because God has shown it to them." Everyone knows enough about God to know that we owe Him complete allegiance and obedience. That's a very unappealing idea to sinners.
This means that atheists and agnostics don't reject the existence of God because of facts and logic. People reject the existence of God, because they don't want to deal with God. This is why apologetic methods that focus on providing evidence (known as "Evidentialism") are generally not very effective. You can't argue someone into the kingdom of heaven with facts and logic and reason. You can point out the inconsistencies in a person's own worldview, but until someone humbles themselves before the Lord, all the evidence in the world would be insufficient to convince him.
We also need to recognize how this dynamic works to a lesser extent in the lives of Christians. We all naturally avoid the truths that we find uncomfortable or undesirable. We like to hear that which makes us feel good about ourselves, and we don't like to hear that which rubs us the wrong way. We often look for ways to explain away uncomfortable truths. As someone once said, the truth sounds hateful to those who hate the truth. But biblical wisdom involves the humility to receive correction and instruction cheerfully. "Whoever heeds instruction is on the path to life, but he who rejects reproof leads others astray" (Prov. 10:17; see also 13:1, 18; 15:5, 32; 19:20). This kind of wisdom begins with admitting our need for wisdom and seeking out godly wisdom wherever it may be found.
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